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AOPPs also stimulate ROS production in podocytes, potentially through proteins such as CCAAT/enhancer binding protein (C/EBP) and glucose-regulated protein 78 (GRP78), resulting in podocyte apoptosis [58]

We identified new users of GLP-1 RAs (exenatide, dulaglutide, liraglutide, or semaglutide) and DPP-4is (sitagliptin, saxagliptin, linagliptin, or alogliptin) based on first dispensed prescription for 1 of these drugs in the VHA with a look-back period of 6 months

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Effect of initial combination therapy with sitagliptin, a dipeptidylpeptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes