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The capacity to develop oxidative stress, arrhythmias, and HF are all associated with, and at least partly driven by, intracellular cardiomyocyte Na + and Ca 2+ concentrations [115,116,117]

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Instead, it is localized to intestinal subepithelial myofibroblasts and enteroendocrine cells
Patients using direct oral anticoagulants may not require routine laboratory monitoring in the same way, but clinicians still evaluate symptoms, medication adherence, and possible side effects

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