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The findings show that patients who underwent sleeve gastrectomy or gastric bypass lost approximately five times more weight over two years than those taking GLP-1 medications.

Our models assume that the biological activity of a peptide is dictated by its primary sequence, which we represent using simple one-hot encoding 25,26,27

Finally, the potential effectiveness of new generation GLP-1 RA in terms of the dose- and exposure time-response still deserves further explorations
Setoyama D, Kato TA, Hashimoto R et al

Result: high adherence, slower initiation, lower commercial upside for premium brands
Circulation 2024;150:1288-98.ArticlePubMed 113
