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In total, 529 pregnancies were exposed to GLP-1 RAs during the periconceptional period

Cosmos Study November 13, 2025 Dual-Team Study Team A:Kersten Bartelt, RNDan GreerEmily Higgs Team B:Louis Kazaglis, MDTed Stamp Key Findings Among patients with polycystic ovary syndrome (PCOS), the median one-year weight change was an 11.5% loss for those treated with a GLP-1, compared to a 1.9% loss among those treated with metformin

GLP-1 Muscle Loss Risk Calculator GLP-1 receptor agonist medications such as semaglutide and tirzepatide may produce significant weight loss, and research suggests that 25 to 40 percent of the weight lost may come from lean body mass rather than fat alone

doi: 10.1139/y69-020

Treatment patterns and associated factors in 14 668 people with type 2 diabetes initiating a second-line therapy: results from the global DISCOVER study programme