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Of these, two studies ( N = 16 and N = 46, respectively) observed a positive association between the use of exenatide, liraglutide or dulaglutide and weight loss as well as HbA1c at 16 weeks 149 and 1 year 150 , while for the smaller one ( N = 7) this association was not significant 148
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Thus, there may be competitionif endogenous GLP-1 is already occupying a receptor, then the fluorescently tagged GLP-1R agonist may not attach and label it
