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PubMed GLP-1 decision path Use this page to decide if a provider review is the right next step Direct answer Tirzepatide and Antidepressants: Safe to Combine

[DOI] [PMC free article] [PubMed] [Google Scholar] 206.Lamos EM, Malek R, Davis SN

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Refrigerated Storage : Unopened tirzepatide pens must be stored in a refrigerator at 36F to 46F (2C to 8C)

Most GLP-1 side effects develop within the first few days to weeks of initiating treatment or a dose increase
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