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Introduction Significant reductions in cardiovascular events, all-cause mortality, and the advancement of kidney disease are demonstrated by important studies such as FLOW

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Tirzepatide was found to improve insulin sensitivity and insulin secretory responses to a greater extent than semaglutide, and this was associated with lower prandial insulin and glucagon concentrations

FDA-approved prescribing information for semaglutide and tirzepatide both indicate use "as an adjunct to a reduced-calorie diet and increased physical activity."What's been missing is the actuarial proof

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