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To ensure proper absorption, Semaglutide is given as a subcutaneous injection meaning its injected into the fat layer just beneath the skin

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Recent hypotheses suggest that GIP induces appetite suppression through independent receptors in the brain, mitigates gastrointestinal side effects of GLP-1 action, and prevents desensitization of GLP-1 receptors, thereby acting as a biased GLP-1RA [87]

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