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Using the efficacy estimand (treatment-adherent analysis), the 36 mg dose achieved 12.4% average weight loss, equivalent to approximately 27.3 pounds

Employers who win in this space: Lead with behavior change Set medication boundaries Require outcome tracking Build a clinical off-ramp With the right design, covering GLP-1s becomes more than a benefit it becomes a business case for long-term health, productivity, and cost control

Once beneficiaries reach their out-of-pocket maximum (set at $2,400 in 2027), they will pay $0 for their medications, including for model drugs

Body recomposition means reducing fat while preserving or improving lean muscle

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Additionally, preclinical research suggests GLP-1 agonists may inhibit nuclear factor-kappa B (NF-B) signaling, a central pathway in inflammatory responses