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GLP-1 is released from L cells, which are mainly located at the ileum, the distal part of the gastrointestinal tract, and is triggered by neuronal or hormonal stimulation and direct nutritional components, including carbohydrates, amino acids, proteins, and fatty acids [15,16,17,18]

Since this medication can slow gastrointestinal motility, staying well-hydrated is essential to help soften stools and promote smoother bowel movements

10.1016/j.expneurol.2020.113377 Exp

Given that different GLP-1 receptor agonists have different dosing recommendations (Table 1), it is important that patients switching between such agents are counseled on any applicable changes to their previous regimen