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Yadav HM, Jawahar A (2023) Environmental Factors and Obesity

JACC CardioOncol

Critically, neither the original 2021 meta-analysis nor the 2025 JAHA study found a significant association between GLP-1 medications and pulmonary embolism

Blocked arteries in the heart (coronary artery disease) High blood pressure Changes in the structure of the heart, often due to cardiomyopathy Hyperthyroidism: overactive thyroid gland Hypothyroidism: underactive thyroid gland Drug abuse Certain supplements and medications, such as cold and allergy drugs without a prescription from a healthcare professional Scarring of the hearts tissue due to prior heart attack What are the symptoms of arrhythmias

This data suggests potential protective ophthalmic effects of anti-obesity GLP-1 therapies for several ophthalmic conditions in non-diabetic patients that warrant further mechanistic and longitudinal investigation