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[4] [6] The SmPC for tirzepatide (Mounjaro), a dual GIP/GLP-1 receptor agonist, similarly documents modest mean heart rate increases

Individual results vary based on dose tolerance, adherence, lifestyle factors, and genetics
doi: 10.1093/hmg/ddi024 177 PoetaL.FuscoF.DrongitisD.ShoubridgeC.ManganelliG.FilosaS.et al

Why Microdosing Works Better for Longevity Minimized Side Effects : Nausea, vomiting, constipation, and fatigue are common at higher doses
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However, consult a primary care physician before starting, especially if you have health conditions (e.g., thyroid issues, caffeine sensitivity) or are on medications
