sglt2 inhibitors and glp 1 receptor agonists GLP-1 in Kidney Transplantation: A Systematic Review and Meta-Analysis Little is known about the
Description
In the CNS, endogenous GLP-1 acts primarily through vagal afferent signaling, transmitting information from the gastrointestinal tract to the brainstem [123, 124]
The observed clinical benefits appear to stem primarily from weight loss rather than direct analgesic mechanisms
Nature 645, 712721 (2025)
10.2147/DDDT.S58459 98 LeaM
And it's a growing problem, with more than 40% of U.S
Saxagliptin is not recommended in patients with ESRD, while alogliptin and sitagliptin can be used at doses of 6.25 mg and 25 mg respectively
