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More people than ever are taking GLP-1 receptor agonistsdrugs like Ozempic (semaglutide), Wegovy, and Mounjaro

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Therefore, although DPP-4 inhibitors have attractive clinical features, the benefits that might be expected from GLP-1 signaling may be undermined by their actions to enhance SDF-1.

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While this persistence rate is a marked improvement over the 10% observed for obesity-indicated GLP-1s, it still leaves 76% of potential demand unrealized