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The appearance of an EM rash can vary, but it usually begins at the site of the bite after around a week and gradually expands in size up to about 12in

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Several significant metabolite-microbe relationships were also revealed, including the glycine strong positive association with Clostridium (Zhuang et al., 2018) and homocysteine positive correlation with Lachnospira , Clostridium , and Haemophilus and its negative correlation with Corynebacterium and Lachnospiraceae (Zhuang et al., 2018)

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