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For patients who achieve significant reduction in food noise with GLP-1 therapy, questions about long-term management arise

Sustained Exendin-4 secretion through gene therapy targeting salivary glands in two different rodent models of obesity/type 2 diabetes

273-275 Nutrient supplementation with fiber, resistant starch, and unsaturated fats are the most studied supplements in both animal studies and small-scale human trialsoften showing increased circulating GLP-1 concentrations and associated metabolic improvements