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While hormonal IUDs like Mirena can slightly increase the risk of breast cancer, the overall benefits of hormonal contraception outweigh the risks Interactions with Medications or Treatments Medications That May Affect Hormonal Efficacy Some types of medications such, as rifampin, carbamazepine and phenhytoin can lessen the impact of Mirenas part Patients should let their healthcare providers know about all the medicines they are taking simultaneously

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