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In a 2022 study of tirzepatide participants who took a weekly 15 mg dose lost an average of 20.9% of their body weight over 72 weeks, compared with 3.1% in the placebo group

Knowing the difference matters

In a 16-week randomized study of 30 obese men with functional hypogonadism who had responded poorly to lifestyle measures, liraglutide raised total testosterone by an average of 2.6 nmol/L and significantly increased LH and FSH a pattern suggesting the HPT axis itself recovered rather than testosterone simply being replaced (Jensterle et al., 2019, Endocrine Connections )

Compounded tirzepatide is more affordable, but still represents a meaningful investment

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In certain embodiments, the subject also has one or more weight-related comorbid conditions such as T2D, hypertension and/or dyslipidemia