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Mikawa Y, et al
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Contraindications and Drug Interactions Colesevelam treatment is contraindicated in patients with a history of bowel obstruction and is cautioned in those with a history of gastrointestinal motility disorders (i.e., gastroparesis) or gastrointestinal surgery (413,424)
Retatrutide is still in clinical trials but is showing promising results
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Others prefer injecting at bedtime to sleep through the initial wave of side effects
