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139 Therefore, the use of MSCs could gradually become a good alternative for the treatment of UC

22 It is now acknowledged that inflammation exacerbates disease progression and symptoms in these conditions

Leptin levels typically decrease after weight loss, which is hypothesized to drive increased hunger and, as a result, weight regain

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Subclinical reductions in protein intake, micronutrient availability, or redox precursor turnover may therefore influence long-term metabolic resilience even without overt deficiency syndromes
Excess body weight remains one of the strongest drivers of insulin resistance
