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Research indicates that GLP-1 also has significant effects on cardiovascular function, including the modulation of heart rate and blood pressure, which further underscores its therapeutic potential beyond glycemic control [41]

This is similar to other obesity treatments

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Bupropion promotes weight loss through central nervous system mechanisms

these drugs were made from the venom of the Gila lizard because the reptiles saliva contains the intestinally secreted peptide GLP1, and for some reason, it is more stable in lizards than humans

Given the previous report of hypersensitivity to liraglutide without a similar reaction to semaglutide, it is possible that other drugs in the GLP-1 agonist class may not cause the same reaction in these patients and may be used as an alternative