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For daily GLP-1 medications, taking them in the evening might help you sleep through peak nausea periods, though this effect may be limited for weekly injections due to their long half-life

Incretins are gut-derived peptides released after food intake, particularly in response to glucose and dietary fats

doi: 10.1161/CIRCULATIONAHA.119.044235

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Despite rising heterogeneity between the two included studies due to different patient populations, this confirmed the efficacy of retatrutide in diabetics and nondiabetics