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Key takeaway: GLP-1 RAs do not appear to increase pancreatitis risk, and may be associated with improved outcomes if pancreatitis occurs.

The GLP-1 market has faced supply constraints in recent months as drugs like Ozempic and Wegovy continue to skyrocket in popularity.

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Here, we investigated the contribution of lipolytic and oxidative changes in white adipose tissue (WAT) to the weight-lowering effect induced by the GLP-1 receptor (GLP-1R) agonist exenatide (exendin-4) in mice

Both produce clinically meaningful weight loss

One of the most important drug targets to emerge has been the Glucagon-like peptide-1 (GLP-1) and its receptor (GLP-1R)