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They dont simply reduce appetite they alter hormonal signaling, metabolism and the brains relationship with food

Long-acting exenatide does not prevent cognitive decline in mild cognitive impairment: a proof-of-concept clinical trial

This is a process where repeated stimulation of neural pathways makes them more responsive over time

However, some patients report slight differences in how the injection feels, injection site reactions, and post-injection side effect patterns when changing formulations
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