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Most significant weight reduction occurs during months 26 as your body adapts and your dose may increase

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Direct nutrient stimulation may induce the initial release of GLP-1 from small intestinal EECs, while large intestinal EECs likely release GLP-1 via a neural hormonal reflex or from microbe-derived metabolites, although this remains to be explored 93,99 (see the Gut microbiotabrain connection section)

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Both treatments are FDA-approved and safe when administered under proper medical supervision

Table of Contents What Are GLP-1 Receptor Agonists and How Do They Work