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With increasing weight loss, osteoporosis risk increased in both groups, and the GLP-1 risks were generally similar to or higher than the non-GLP-1 weight loss medication risks

Liraglutide Effect and Action in Diabetes (LEADTM) trial

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The efficacy and safety of GLP-1 agonists in PCOS women living with obesity in promoting weight loss and hormonal regulation: A meta-analysis of randomized controlled trials