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Why These Results Are Meaningful A New Level of Weight Change The degree of weight reduction seen in TRIUMPH-4 exceeds that observed with many earlier investigational agents and has drawn attention within the metabolic health community

Up to 50 % of mid-pubertal boys develop temporary breast enlargement, and three-quarters resolve within two years without intervention

Conflict of Interest The author(s) do not have any conflict of interest

Data supporting this systematic review are available upon reasonable request to the corresponding author at ([email protected])

Already, the grocery sector has lost an estimated 136 million in food and drink spending, with GLP-1 users cutting their grocery spend by 2.2 percentage points more than non-users