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doi: 10.1016/j.ijcard.2011.09.039 260 McGuireDKShihWJCosentinoFCharbonnelBCherneyDZIDagogo-JackSet al

These symptoms are usually worst during the first few weeks and during each dose increase, then gradually improve as the body adapts

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Weight loss during this period is often linear and consistent, roughly one to two pounds per week at the maintenance dose

That is especially true for refrigerated products and products with multiple dose strengths, due to factors like ordering practices and incentives, cold chain logistical considerations and retailer capacity constraints

Hemodynamic effect of a single dose of glucagon-like peptide 1 receptor (GLP-1R) agonist liraglutide in patients with diabetic kidney disease