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Description
Severe or persistent side effects : If you develop intolerable nausea, vomiting, or abdominal pain, your GP may recommend temporarily pausing treatment to allow symptoms to resolve before restarting at a lower dose

[DOI] [PMC free article] [PubMed] [Google Scholar] Philippe J, Drucker DJ, Knepel W, Jepeal L, Misulovin Z, Habener JF
Fibre BDA (British Dietetic Association)

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While often asymptomatic in the early stages, advanced colon cancer symptoms are stomach pain, stomach distention, and weight loss

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