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doi: 10.4254/wjh.v15.i5.609

The approval is supported by results from the Phase 3 POETYK PsA1 and POETYK PsA2 trials, which demonstrated statistically significant improvements in ACR20 Response and other key disease outcomes compared with placebo, while maintaining a safety profile consistent with earlier studies

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While retatrutide shows immense promise, considerations regarding cost and the quality of weight loss beyond BMI reduction warrant further investigation

These payer mechanisms reflect limited public reimbursement coverage for obesity pharmacotherapy under the National Health Insurance system

(b) the process by which the compounded drugs are manufactured have not been reviewed by the FDA