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Tirzepatide, a dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist, has also been studied for the treatment of MASLD

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Gao et al., 2011)

Understanding the level of weight loss achieved with each can help guide medication selection

Some users find that while they slept through the initial peak, they wake up with lingering low-grade nausea that takes a few hours to resolve

Protease-Independent Metabolic Effects of DPP-4 While some of the effects of DPP-4and, arguably, most, if not all of the pharmacological effects of DPP-4 inhibitors (38)on glucose homeostasis are mediated primarily by modulating the activity of the incretin hormones, it has also been proposed that DPP-4 may influence metabolic control via mechanisms which do not necessarily involve its catalytic activity, with several studies noting a positive correlation between DPP-4 and insulin resistance (79, 81, 88)