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All existing research has been conducted in mice, with no long-term human safety trials and no established safe doses for humans
[DOI] [PubMed] [Google Scholar] 35.Packer M, Lam CSP, Lund LH, et al
Another study published in JAMA Ophthalmology in February of 2025 analyzed data from 37.1 million adults with type 2 diabetes across 14 databases in the U.S
Taylor K
While this effect is usually mild, it may make some people more susceptible to dehydration or an imbalance of electrolytes like sodium and potassium
Eat balanced, nutrient-dense meals even if your appetite is reduced
