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Tirzepatide's dual GLP-1/GIP activation produces stronger metabolic effects than single-agent medications, with clinical trials showing average 20% to 22% body weight loss over six months at therapeutic doses

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27 Other side effects and risks of GLP-1s include: Dizziness Mild tachycardia (increased heart rate) Headaches Injection site reactions, such as itchiness and redness Hypoglycemia (low blood sugar) Severe Risks & Contraindications While less common, GLP-1s can pose severe risks such as intestinal blockage and gastroparesis 28 , which refer to the delay in gastric emptying without evidence of mechanical obstruction

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Treatment goals focus on glycemic control, weight management, and comprehensive cardiometabolic risk reduction rather than targeting inflammatory markers

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If your semaglutide has been left out for more than two hours or frozen, discard it immediately and request a replacement from PlexusDx

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