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doi: 10.1515/jpem-2013-0180 124 Festen D a.MWeversMLindgrenACBhmBOttenBJWitJMet al

GLP-1 agonists can be life-changing, but they work best as part of a holistic plan

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That doesn't necessarily mean the first medication "failed." People respond differently to GLP-1 drugs, and some tolerate or respond to one medication better than another
Exendin-4 inhibits hepatic lipogenesis by increasing -catenin signaling

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