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Gastrointestinal effects The most common side effects are GI-related, and they follow a predictable pattern tied to dose escalation

The absence of readily available, data-driven assessments of effectiveness represents a significant limitation

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Together, these observations demonstrate marked variability in the ability of short-term metformin to lower rates of gluconeogenesis under basal or clamp conditions in youth and adults with modest hyperglycaemia

Some people may lose 1-2 pounds

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