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2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Obesity Society
Fertility and pregnancy-associated -cell proliferation in mice deficient in proglucagon-derived peptides

Food and Drug Administration (FDA) approved Ozempic with a new indication: to reduce the risk of kidney disease worsening and cardiovascular death in adults with type 2 diabetes and chronic kidney disease a major clinical milestone demonstrating broader therapeutic value beyond glycemic control

When GLP-1 receptor agonists like semaglutide or tirzepatide bind to these receptors, one of their effects is slowing the rate at which food moves from the stomach to the small intestine
Subsequently, YGD has been demonstrated to produce a robust acute effect on caloric intake and meal duration, suggesting that YGD strengthens within-meal satiation, an effect that may be mediated by the previously reported changes in gastric emptying [67]

In women with PCOS, these changes can restore menstrual regularity and ovulation