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Loperamide typically lacks central opioid effects at recommended doses (28 mg/day) due to low oral bioavailability and P-glycoprotein efflux 37
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We must have lots of it to use as, like, a reference
doi: 10.1136/bmj-2023-076410 [DOI] [PMC free article] [PubMed] [Google Scholar]
Those who might look elsewhere include people who prefer FDA-approved finished products only
(1) Peptides play an important role in many internal processes and biological functions , including hormone regulation, cell signaling, immune response, and more
