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363 According to previous reports, exendin-4, a GLP-1RA, has the potential to inhibit LPS-induced osteoclast formation and bone resorption in vivo

Safety and quality notes Compounded GLP-1 medications are made by licensed compounding pharmacies, and many telehealth programs partner with accredited facilities

Evidence on Thyroid and Pancreatic Cancer Risks Review findings suggest that while early studies sparked fears of GLP-1 RAs increasing cancer risks or exacerbating malignancy outcomes, these fears have now been largely tempered by a growing body of reassuring and even positive data

Ann Intern Med [Internet]

If you have concerns about how GLP-1s might interact with your specific hormone situation, thats a conversation for your doctor, not the internet

However, a low-calorie diet along with GLP-1 agonist drugs can also lead to loss of lean mass, emphasizing the need for protein intake with resistance training to preserve muscle mass