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But their side effect profiles differ dramatically

However, Ramracheya et al

Gill, MD About 6% of adults in the United States take GLP-1 agonists for Type 2 diabetes or weight loss

Recognizing these rare cases is essential, as targeted therapies (e.g., setmelanotide) may be effective in specific genotypes

Previous evidence had largely come from preclinical studies, registry analyses, or smaller clinical investigations

Quintela, J
