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WD increased, whereas GE2 reduced, body weight in both sexes As expected, four weeks of WD consumption resulted in weight gain, compared to SD in both sexes (F( 1, 132 ) = 18.895, p 2 = 0.125, p = 0.000

This provides a clear view into how these therapies are being integrated into diabetes care at scale and highlights the value of Marketplace data for tracking treatment adoption and patient outcomes in real time (Figure 1)

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Furthermore, increased levels of circulating free fatty acids, inflammatory cytokines (TNF-, IL-1, IL-6) and chemokines increase BBB permeability

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TNF- inhibitors such as Infliximab and Etanercept did not show benefits in chronic heart failure due to the worsening of the clinical status and some serious adverse effects, such as upper respiratory tract infections [18, 19]