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Front Endocrinol (Lausanne) 14:1240263 [DOI] [PMC free article] [PubMed] [Google Scholar] 17.Sattar N, Neeland IJ, Dahlqvist Leinhard O, Fernandez Lando L, Bray R, Linge J et al (2025) Tirzepatide and muscle composition changes in people with type 2 diabetes (SURPASS-3 MRI): a post-hoc analysis of a randomised, open-label, parallel-group, phase 3 trial

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Both glucose concentration and the rate of change are included in the data

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Addictive substances rewire this pathway to cause the body to crave more of the substance so the behavior is repeated

The construct was expressed in Spodoptera frugiperda ( Sf 9) insect cells (Invitrogen) with Bac-to-Bac Baculovirus system (Invitrogen) and cells were infected at a density of 2 10 6 cells per mL and collected 48 h after infection