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It is generally avoided in individuals with a personal or family history of medullary thyroid carcinoma (MTC) or MEN2, a history of pancreatitis, or certain severe gastrointestinal conditions

Notably, all biologic therapies for obesity should be used as adjuncts to optimal lifestyle modification

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Semaglutide is also available as injectable formulations, including Ozempic and Wegovy , which are widely recognized for their efficacy in the management of T2DM and obesity

Thyroid hormone replacement requires consistent, predictable absorption to maintain stable TSH levels and avoid symptoms of under- or over-replacement