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If patients experience persistent nausea or inability to maintain adequate oral intake, they should contact their prescribing clinician, as dose adjustment may be necessary

The surge in demand for GLP-1RA has resulted in intermittent global shortages and gaps in therapy due to variable medication availability
2.3.3 Extra-endocrine expression of taste receptors Beyond EECs, it is also important to mention that taste receptors may also be present in the brush cells, a subgroup of solitary chemosensory cells found in the nasal cavity and other regions of the gut, especially where food passes from the fundus to the corpus, and digestive process are initiated, where expression of TAS1R1, TAS1R3, and a-gustducin are involved, suggesting a role in amino acid sensing (60, 78, 79)

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