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Most importantly, the addition of a second drug results in an additive improvement in glycemic control

In addition, tolbutamide and chlorpropamide, in certain susceptible individuals, is associated with alcohol-induced flushing (20)

Alcohol, caffeine, and other modifiable triggers Two substances that many people consume daily interact with both tirzepatide and migraine susceptibility: alcohol and caffeine

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Do not stop Rybelsus without discussing with your diabetes team, as your blood glucose may rise and your treatment plan may need adjustment