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PKA-mediated induction of IRS-2 expression also promotes -cell growth in response to GLP-1, 53,62 and PKA mediates the action of GLP-1 to promote translocation of transcription factor PDX-1 to the nucleus, thereby enhancing the differentiated state of -cells

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Semaglutide tablets are part of a class of medications known as GLP-1 receptor agonists

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