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People with clinical obesity requiring significant medical intervention- GLP-1 medications produce 15 to 20% body weight reduction in clinical trials

CRC Press
Historically, each GLP-1 dollar was split roughly like this: Pharma (Lilly/Novo): ~60% PBMs, insurers, wholesalers, pharmacies: up to 40% That 40% is not value-added

Berberine and GLP-1 drugs work through complementary mechanisms

21 August 2023

Due to their various modes of action, which include vasodilation, natriuresis, glucose and weight control, and direct cardioprotective effects, GLP-1 receptor agonists have therapeutic potential for treatment of heart failure (41)