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According to the FDA prescribing information for Wegovy, semaglutide is used with a reduced-calorie diet and increased physical activity for chronic weight management when medically appropriate

503B: A Quick-Guide to Compounding Pharmacy Designations & Regulations, accessed December 19, 2025, Regulatory Framework for Human Drug Compounding FDA, accessed December 19, 2025, FDAs Authority to Regulate Drug Compounding: A Legal Analysis EveryCRSReport.com, accessed December 19, 2025, THOMPSON v

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Key examples: Diabetes + CKD = diabetic CKD (E11.22) no explicit caused by diabetes statement needed Diabetes + neuropathy = diabetic neuropathy (E11.4x) Diabetes + retinopathy = diabetic retinopathy (E11.3xx) Diabetes + periodontal disease = diabetic periodontal disease (E11.630) However, the provider must not document that the condition is NOT related to diabetes

Blood tests for thyroid function, ferritin, vitamin D, folate and B12 can help clarify what is going on

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