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Cardiovasc Diabetol 24 , 70 (2025)

They work by replicating a natural hormone called incretin, which boosts GLP-1 to help regulate blood sugar, fulfil satiety and manage weight

Looking at those who've tried then gone off a GLP-1: "The data suggests that by 18 months, people will have regained all of the weight," said Cohen, who says he'll often look at what people are saying on Reddit to get more insight

approvals, so Canadians living with type 2 diabetes may be waiting a little longer

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Tirzepatide is also less effective at reducing body weight in T2D patients compared to patients without (15.7% weight loss, SURMOUNT-2 and 22.5% weight loss, SURMOUNT-1, respectively)
