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Eli Lilly is developing a next-generation GLP therapy called retatrutide that targets three receptors: GLP-1, GIP, and glucagon

They address the underlying mechanism, semaglutide slowing gastric motility, which in turn slows colonic transit time

NHS and Manufacturer Recommendations: Use a barrier method (like condoms) for at least 4 weeks after starting Mounjaro Also apply the 4-week barrier rule after each dose increase Consider switching to non-oral forms of contraception (e.g., patch, IUD, implant) 2

Stay updated on rollout timelines and eligibility to maximize savings

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Certain lifestyle changes may help reduce some Wegovy side effects