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Due to the drug's popularity recently for weight loss, there has been a short supply for people who use it as a pre-diabetes drug

On-demand access to recorded presentations from this session will be available to registered participants of the 85 th Scientific Sessions through August 25

Gastrointestinal: Acute pancreatitis, hemorrhagic and necrotizing pancreatitis sometimes resulting in death, ileus General Disorders and Administration Site Conditions: Allergic reactions: rash and pruritus Hepatobiliary: Elevations of liver enzymes, hyperbilirubinemia, cholestasis, cholecystitis, cholelithiasis requiring cholecystectomy, hepatitis Immune system: Angioedema and anaphylactic reactions Metabolism and nutrition: Dehydration resulting from nausea, vomiting and diarrhea Neoplasms: Medullary thyroid carcinoma Nervous system: Dysgeusia, dizziness Pulmonary: Pulmonary aspiration has occurred in patients receiving GLP-1 receptor agonists undergoing elective surgeries or procedures requiring general anesthesia or deep sedation

Smoother Titration and Adaptation The standard dose escalation schedule can sometimes be too rapid for highly sensitive individuals

This can include variations in dosage, delivery methods, and formulations that may not be available in standard products

Additionally, there was GLP1 RA expression in tumor cells and infiltrating immune cells in human TNBC specimens, suggesting potential immunomodulatory effects that can impact treatment response